Autonomous Vehicles an overview on system, cyber security, risks, issues, and a way forward

This chapter explores the complex realm of autonomous cars, analyzing their fundamental components and operational characteristics. The initial phase of the discussion is elucidating the internal mechanics of these automobiles, encompassing the crucial involvement of sensors, artificial intelligence (AI) identification systems, control mechanisms, and their integration with cloud-based servers within the framework of the Internet of Things (IoT). It delves into practical implementations of autonomous cars, emphasizing their utilization in forecasting traffic patterns and transforming the dynamics of transportation. The text also explores the topic of Robotic Process Automation (RPA), illustrating the impact of autonomous cars on different businesses through the automation of tasks. The primary focus of this investigation lies in the realm of cybersecurity, specifically in the context of autonomous vehicles. A comprehensive analysis will be conducted to explore various risk management solutions aimed at protecting these vehicles from potential threats including ethical, environmental, legal, professional, and social dimensions, offering a comprehensive perspective on their societal implications. A strategic plan for addressing the challenges and proposing strategies for effectively traversing the complex terrain of autonomous car systems, cybersecurity, hazards, and other concerns are some resources for acquiring an understanding of the intricate realm of autonomous cars and their ramifications in contemporary society, supported by a comprehensive compilation of resources for additional investigation. Keywords: RPA, Cyber Security, AV, Risk, Smart Car

Aboriginal and Non-Aboriginal Students Learn About Natural Health Products from Different Information Sources

Natural health products (NHPs) include naturally derived botanical and nonbotanical products. Past research indicates a high prevalence of NHPs use amongst adults in the United States and Canada but does not clearly characterize NHPs use amongst students, ethnic variations of such use, or how users learn about NHPs. We hypothesize that there is a difference between Aboriginal and non-Aboriginal students in how they learn about NHPs. To investigate this question, we conducted a cross-sectional study at First Nations University of Canada and the University of Regina, Saskatchewan, Canada, during the fall of 2011. Aboriginal (n=214) and non-Aboriginal (n=749) students participated in the 28 question survey. Our results indicate that Aboriginal students who use NHPs are found in all age groups, are mostly female, are smokers and nonsmokers, and learn about NHPs from Elders and healers. Compared to nonAboriginal students, Aboriginal students rely significantly less on alternative and conventional health providers, electronic media, print media, and advertising as their sources of information about NHPs. Thus, Aboriginal students use Elders or healers as a primary source of information to learn about NHPs, as compared to non-Aboriginal students. Future work should investigate the role of Elder traditional educators to convey NHPs information directed specifically to Aboriginal university students

Native/Aboriginal Students use Natural Health Products for Health Maintenance More so than Other University Students

Background and aim: University student use of Natural Health Products (NHP) for health maintenance (HealthM) is assessed in Canada. We hypothesize greater use of NHP by Native/Aboriginal and female students. Demographic predictor variables and the top ten NHP used are determined. Methods: A cross-sectional survey of 963 students (n=212 Native/Aboriginal; n=751 non-Native/Aboriginal) was conducted. χ2 and Fisher’s exact tests analyzed group differences. Multiple logistic regressions determined predictor variables of NHP use. Results: Of 963 surveyed students, 268 (27.8%) used NHP for HealthM, while 695 students (72.2%) did not. More Native/Aboriginal students used commercial tobacco (47% vs. 13%, P\u3c0.001) and NHP (67% vs. 45%, P\u3c0.001) than non- Native/Aboriginal students. Gender was not associated with NHP use (P=0.527). Canadians used echinacea more than non-Canadians (Odds Ratio [OR]=4.96; 95% Confidence Interval [CI]: 1.2-21.0). Ginger (OR=0.39; 95% CI: 0.2-0.78) and garlic (OR=0.28; 95% CI: 0.13-0.6) were popular amongst non-Canadians. Native/Aboriginal students used homeopathics (OR=39.9; 95% CI: 8.6-185.4) and rat root (OR=56.73; 95% CI: 6.91-465.8). Chamomile was less used by males (OR=0.33; 95% CI: 0.13-0.83) and used more by upperclassmen (OR=2.6 95% CI: 1.3-5.3). Conclusion: Homeopathics and rat root are popular amongst Native/Aboriginal students. Garlic and ginger are popular amongst non-Canadians than Canadian students; however, more Canadians used echinacea for HealthM than non-Canadians. Chamomile is less popular amongst males. Commercial tobacco is used more by Native/Aboriginal students. Predictors of NHP use are: Native /Aboriginal and upperclassman

Molecular docking supported investigation of antioxidant, analgesic and diuretic effects of Costus speciosus rhizome

ABSTRACT. The aim of the current study was to analyze the polyphenols and determines the antioxidant, analgesic and diuretic properties of the methanolic extract of C.speciosus rhizome. DPPH and ferric reducing antioxidant power (FRAP) assays were used to determine the antioxidant activity. Acetic acid-induced writhing and formalin-induced licking experiments were used to assess the analgesic effect. The total phenolic, flavonoid and flavonol contents were found 51.73± 0.25 mg GAE/g dry weight, 3.41± 0.07mg QE/g dry weights and 44.19± 2.24 mg QE/g dry weight, respectively. The plant extract exhibited weak antioxidant activity in the DPPH and FRAP assays, with an IC50 value of 1699±62 μg/mL and an EC50 value of 125±2 μg/mL, respectively. The extract significantly reduced the number of writhes at both doses (200 and 400 mg/kg body weight) as compared to the control. The extract (400 mg/kg) also significantly reduced the percent inhibition of licking by 31.96 and 62.69% compared to the control in the early and late phase, respectively. Compared to the standard drug furosemide, the plant extract also showed a weak diuretic effect. The docking study supported the analgesic activity of rhizome extract. The potent analgesic activity of the plant extract justifies the traditional and medicinal aspects.   KEY WORDS: Costus speciosus, Analgesic activity, Diuretic effect, Molecular docking Bull. Chem. Soc. Ethiop. 2022, 36(3), 627-640.                                                                 DOI: https://dx.doi.org/10.4314/bcse.v36i3.12 &nbsp

Cosine similarity-based algorithm for social networking recommendation

Social media have become a discussion platform for individuals and groups. Hence, users belonging to different groups can communicate together. Positive and negative messages as well as media are circulated between those users. Users can form special groups with people who they already know in real life or meet through social networking after being suggested by the system. In this article, we propose a framework for recommending communities to users based on their preferences; for example, a community for people who are interested in certain sports, art, hobbies, diseases, age, case, and so on. The framework is based on a feature extraction algorithm that utilizes user profiling and combines the cosine similarity measure with term frequency to recommend groups or communities. Once the data is received from the user, the system tracks their behavior, the relationships are identified, and then the system recommends one or more communities based on their preferences. Finally, experimental studies are conducted using a prototype developed to test the proposed framework, and results show the importance of our framework in recommending people to communities

A Multimodality Hybrid Gamma-Optical Camera for Intraoperative Imaging

The development of low profile gamma-ray detectors has encouraged the production of small field of view (SFOV) hand-held imaging devices for use at the patient bedside and in operating theatres. Early development of these SFOV cameras was focussed on a single modality-gamma ray imaging. Recently, a hybrid system-gamma plus optical imaging-has been developed. This combination of optical and gamma cameras enables high spatial resolution multi-modal imaging, giving a superimposed scintigraphic and optical image. Hybrid imaging offers new possibilities for assisting clinicians and surgeons in localising the site of uptake in procedures such as sentinel node detection. The hybrid camera concept can be extended to a multimodal detector design which can offer stereoscopic images, depth estimation of gamma-emitting sources, and simultaneous gamma and fluorescence imaging. Recent improvements to the hybrid camera have been used to produce dual-modality images in both laboratory simulations and in the clinic. Hybrid imaging of a patient who underwent thyroid scintigraphy is reported. In addition, we present data which shows that the hybrid camera concept can be extended to estimate the position and depth of radionuclide distribution within an object and also report the first combined gamma and Near-Infrared (NIR) fluorescence images.Peer-reviewedPublisher Versio

Prevalence and Causes of Intrahepatic and Extrahepatic Bile Duct Obstruction among the Jaundiced Patients at Riyadh Hospitals Diagnosed by Ultrasound

The aim of this study was to assess the prevalence and causes of bile duct obstruction among patients with jaundice at the ultrasound departments in Riyadh hospitals. Methods and Results: The study included 525 records of jaundiced patients above 18 years old that were referred to the ultrasound department. Data were collected from PACS (Picture Archiving and Communication System) at three different hospitals in Riyadh. Of 525 adult jaundiced patients, 69 had biliary obstruction, a 13% prevalence. In our study, 38(55.1%) cases of obstruction were caused by stones, 14(20.3%) by tumors, 9(13.0%) by inflammation, 5(7.2%) by a nonfunctioning stent, and 3(4.3%) by pnemobilia. Obstructive jaundice occurred significantly more frequently with increasing age. The study revealed no significant difference between gender and the presence of obstruction. More studies with a larger sample size of obstructive jaundice patients are suggested

Alkhurma Hemorrhagic Fever Virus in Ornithodoros savignyi Ticks

Evidence for the tickborne nature of Alkhurma hemorrhagic fever virus (AHFV) is indirect because AHFV has not been detected in arthropods. One Ornithodoros savignyi tick from Saudi Arabia contained AHFV RNA. This is the first direct evidence that AHFV is a tickborne flavivirus and confirms the association between human AHFV cases and tickbite history

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London